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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HEATR1
All Species:
20.61
Human Site:
T745
Identified Species:
34.87
UniProt:
Q9H583
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H583
NP_060542.4
2144
242370
T745
K
K
L
E
S
V
I
T
A
V
E
I
P
S
E
Chimpanzee
Pan troglodytes
XP_001156974
2144
242420
T745
K
K
L
E
S
V
I
T
A
V
E
I
P
S
E
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_536334
2141
242568
T745
K
K
L
E
S
V
I
T
A
V
E
I
S
S
E
Cat
Felis silvestris
Mouse
Mus musculus
NP_659084
2143
242053
T745
R
K
L
K
S
V
I
T
A
V
E
I
P
S
E
Rat
Rattus norvegicus
NP_001101888
2143
241191
T745
K
K
L
K
S
I
I
T
A
V
E
V
P
S
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_422958
2155
244590
C745
K
I
R
N
L
R
A
C
H
P
E
E
E
T
P
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q7SY48
2159
242032
Q741
L
L
Q
A
Y
T
I
Q
P
E
Q
V
S
D
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VM75
2096
237201
V741
R
R
L
Q
F
R
V
V
N
G
S
Q
N
T
Q
Honey Bee
Apis mellifera
XP_393800
2028
231830
T707
L
Q
N
C
N
N
I
T
G
N
N
I
Q
T
A
Nematode Worm
Caenorhab. elegans
Q23495
1650
185210
A391
S
I
L
T
G
D
Q
A
G
T
I
L
K
L
I
Sea Urchin
Strong. purpuratus
XP_794611
1635
181917
C376
E
I
E
F
P
E
G
C
K
E
L
D
L
I
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9C8Z4
2001
224001
L706
N
K
L
Q
K
G
L
L
I
R
E
S
V
S
A
Baker's Yeast
Sacchar. cerevisiae
P42945
1769
200063
S510
G
K
G
Y
K
A
S
S
F
L
T
S
F
F
T
Red Bread Mold
Neurospora crassa
Q7RZM8
1788
196873
L529
V
A
A
N
E
S
N
L
Q
K
F
D
E
A
P
Conservation
Percent
Protein Identity:
100
99.5
N.A.
89.7
N.A.
83.8
84.9
N.A.
N.A.
65.5
N.A.
54.5
N.A.
28.6
30.5
21.1
24.4
Protein Similarity:
100
99.8
N.A.
95
N.A.
92.1
92.7
N.A.
N.A.
80.5
N.A.
73
N.A.
49.4
50.8
38.9
43.2
P-Site Identity:
100
100
N.A.
93.3
N.A.
86.6
80
N.A.
N.A.
13.3
N.A.
6.6
N.A.
6.6
20
6.6
0
P-Site Similarity:
100
100
N.A.
93.3
N.A.
100
100
N.A.
N.A.
20
N.A.
26.6
N.A.
46.6
40
13.3
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
22.4
21.2
23
Protein Similarity:
N.A.
N.A.
N.A.
43.4
40.2
42.2
P-Site Identity:
N.A.
N.A.
N.A.
26.6
6.6
0
P-Site Similarity:
N.A.
N.A.
N.A.
40
20
6.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
8
8
0
8
8
8
36
0
0
0
0
8
22
% A
% Cys:
0
0
0
8
0
0
0
15
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
8
0
0
0
0
0
15
0
8
0
% D
% Glu:
8
0
8
22
8
8
0
0
0
15
50
8
15
0
36
% E
% Phe:
0
0
0
8
8
0
0
0
8
0
8
0
8
8
0
% F
% Gly:
8
0
8
0
8
8
8
0
15
8
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% H
% Ile:
0
22
0
0
0
8
50
0
8
0
8
36
0
8
8
% I
% Lys:
36
50
0
15
15
0
0
0
8
8
0
0
8
0
0
% K
% Leu:
15
8
58
0
8
0
8
15
0
8
8
8
8
8
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
8
0
8
15
8
8
8
0
8
8
8
0
8
0
0
% N
% Pro:
0
0
0
0
8
0
0
0
8
8
0
0
29
0
15
% P
% Gln:
0
8
8
15
0
0
8
8
8
0
8
8
8
0
15
% Q
% Arg:
15
8
8
0
0
15
0
0
0
8
0
0
0
0
0
% R
% Ser:
8
0
0
0
36
8
8
8
0
0
8
15
15
43
0
% S
% Thr:
0
0
0
8
0
8
0
43
0
8
8
0
0
22
8
% T
% Val:
8
0
0
0
0
29
8
8
0
36
0
15
8
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
8
8
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _